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PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1
Descriptors Found:
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DeCS
Descriptor
English
:
Protein Tyrosine Phosphatase, Non-Receptor Type 1
Descriptor
Spanish
:
Proteína Tirosina Fosfatasa no Receptora Tipo 1
Descriptor
Portuguese
:
Proteína Tirosina Fosfatase não Receptora Tipo 1
Tree Number:
D08.811.277.352.650.775.300.100
D12.644.360.585.100
D12.776.476.564.100
Definition
English
:
A subtype of non-receptor
protein tyrosine phosphatases
that includes two distinctive targeting motifs; an N-terminal motif specific for the
INSULIN
RECEPTOR, and a C-terminal motif specific for the SH3 domain containing
proteins
. This subtype includes a hydrophobic domain which localizes it to the
ENDOPLASMIC RETICULUM.
History Note
English
:
2008
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52696
Unique Identifier:
D054562
Occurrence in VHL
:
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CID-10
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